Pain News and Research

Latest Pain News and Research

AAN releases Evidence in Focus Article on new gene therapy for Duchenne muscular dystrophy

To help neurologists, clinicians and families understand the current evidence for a new gene therapy for Duchenne muscular dystrophy called delandistrogene moxeparvovec, the American Academy of Neurology (AAN) has issued an Evidence in Focus article, published May 14, 2025, online in Neurology.

14 May 2025

Researchers uncover key role of peri-LC neurons in the brain arousal system

A small cluster of cells deep within our brains, called the locus coeruleus, affects how awake and attentive we are, how we respond to stress, how we cope with anxiety and fear, and how we create memories and learn.

14 May 2025

Predictive tools aim to improve pediatric pneumonia outcomes

Researchers derived pragmatic models that accurately distinguish mild, moderate and severe pneumonia in children, based on evidence from a study performed in 73 Emergency Departments (EDs) in 14 countries through the international Pediatric Emergency Research Network (PERN).

14 May 2025

Can diet ease IBS? A low-FODMAP plan cut symptoms but raised nutrient concerns

A 10-week low-FODMAP diet significantly reduced symptom severity in Saudi adults with IBS, with most shifting from severe to moderate symptoms. However, the restrictive diet also led to declines in several essential nutrients, highlighting the need for professional guidance.

14 May 2025

New candidate compounds show promise for Alzheimer's and pain treatment

A study published in the Journal of Medicinal Chemistry presents a new family of candidate compounds for the treatment of Alzheimer's disease and pain, which have shown promising effects in animal models.

14 May 2025

Once-daily oral treatment shows positive results in first human study for obesity treatment

A first-in-human study of an investigational once-daily oral treatment for obesity (SYNT-101) demonstrated positive preliminary data for the safe and effective redirection of nutrient absorption into the lower intestine, the weight loss and metabolic management mechanism behind gastric bypass surgery.

14 May 2025

Trump’s fast-tracked deal for a copper mine heightens existential fight for Apache

Carrying eagle feathers and chanting prayers, Western Apache runners hit the road on a roughly 80-mile journey this month to try to save their sacred land from being fast-tracked by President Donald Trump into a copper mine.

14 May 2025

Flawed federal programs maroon rural Americans in telehealth blackouts

Ada Carol Adkins lives with her two dogs in a trailer tucked into the timbers off Upper Mud River Road.

14 May 2025

HIV uses circular RNAs to evade immunity and boost replication

In a groundbreaking discovery, researchers from Florida Atlantic University's Charles E. Schmidt College of Medicine have identified a never-before-seen mechanism that enables the human immunodeficiency type 1 virus (HIV-1) to evade the body's natural defenses and use it to support its survival and replication.

13 May 2025

Tirzepatide outperforms semaglutide in weight loss clinical trial

Tirzepatide (trade name Zepbound) promoted greater weight loss in individuals with obesity than did semaglutide (trade name Wegovy) in a clinical trial that compared the safety and efficacy of the injectable drugs.

12 May 2025

City of Hope opens largest outpatient facility to enhance cancer care

As advances in early detection and treatment transform cancer into a chronic disease, City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, opens its largest outpatient facility among its network of 38 U.S. locations.

12 May 2025

Millions of women may be unaware of their risk for cardiovascular-kidney-metabolic disease

Millions of women may be unknowingly living with risk factors for heart, kidney and metabolic disease – interconnected conditions that together drive risk for cardiovascular disease, the leading cause of death among women, according to experts with the American Heart Association, a global force changing the future of health for all.

12 May 2025

Effects of practice standards on opioid prescribing and chronic pain management

In an effort to curb misuse of opioids and prevent overdose deaths, the College of Physicians and Surgeons of British Columbia released a legally enforceable practice standard, Safe Prescribing of Drugs with Potential for Misuse/Diversion, in 2016.

12 May 2025

An Arm and a Leg: A health policy veteran puts 2025 in perspective

News has been coming out of Washington, D.C., since the start of the second Donald Trump administration like water out of a fire hose. It can feel impossible to stay on top of all the changes.

12 May 2025

Australia faces critical medicine shortages amid global supply challenges

About 400 medicines are in short supply in Australia. Of these, about 30 are categorized as critical. These are ones with a life-threatening or serious impact on patients, and with no readily available substitutes.

12 May 2025

Woman with rare genetic disorder delivers healthy baby after complex pregnancy

When Jessica Johnson, 36, began to experience labored breathing and heart palpitations, she quickly made an appointment to see a cardiologist.

11 May 2025

Using gas stoves at home significantly increases cancer risk

A new study in the Journal of Hazardous Materials modeled benzene emissions from the top 5% of gas stoves in U.S. homes, finding elevated cancer risks, especially for children, in poorly ventilated spaces. Using validated simulations, the researchers estimated up to 69 additional leukemia cases annually under high-use, unventilated scenarios.

10 May 2025