Ready to transform preclinical testing with Organ-on-a-chip?

	Drug Discovery
	The latest drug discovery news from News Medical

With global regulations moving towards the phasing out of animal testing for new approach methodologies and awareness that Organ-on-a-chip outperforms traditional in vitro approaches, the technology will become integral to drug discovery.

			Personalized Neoantigen Vaccines: Principles, Technologies, and Clinical Impact Neoantigen vaccines are at the forefront of cancer research, driving personalized immunotherapy and improving outcomes through targeted T-cell activation.

			Artificial intelligence unlocks new frontiers in RNA drug design In the realm of modern medicine, RNA-based therapies have emerged as a promising avenue, with significant advancements in metabolic diseases, oncology, and preventive vaccines.

	New clinical trial offers hope for patients with advanced “dry” age-related macular degeneration Age-related macular degeneration, the leading cause of vision loss and blindness for Americans 65 and older, is a progressive disease affecting central vision.

	Most clinical trials fail to reflect America’s racial and ethnic diversity A new study finds just 6% of clinical trials used to approve new drugs in the U.S. reflect the country's racial and ethnic makeup, with an increasing trend of trials underrepresenting Black and Hispanic individuals.

	Financial barriers drive low participation in cancer clinical trials A study by Case Western Reserve University and University Hospitals researchers has overturned long-held assumptions about why more cancer patients don't enroll in clinical trials that could potentially save their lives.

	Single-dose oral cholera vaccine shows promising results in early clinical trial Clinical trial shows promising results for PanChol, a single-dose oral vaccine aimed at the up to 4 million annual cholera cases worldwide.

	Researchers Find Enzyme That Controls Fat Production, Offering New Drug Target Obesity is a global epidemic and a major cause of morbidity and mortality because it increases the risk for comorbidities, including heart disease and fatty liver disease (MASLD). Rates of these disorders have risen as the world increasingly adopts energy-dense diets and sedentary lifestyles.

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