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Rethinking Mendelian assumptions in inherited retinal degenerations

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.

22 Dec 2025

Remodeling the tumor microenvironment to unlock CAR-T cell potential

Chimeric antigen receptor T (CAR-T) cell therapy has revolutionized hematologic cancer treatment, but its efficacy in solid tumors remains limited by poor infiltration into the complex tumor microenvironment (TME).

22 Dec 2025

Early identification of nutrition risk in ICU patients using artificial intelligence

A new study by researchers at the Icahn School of Medicine at Mount Sinai suggests that artificial intelligence (AI) could help predict which critically ill patients on ventilators are at risk of underfeeding,

22 Dec 2025

Probiotic supplementation restores beneficial gut bacteria in breastfed infants

In recent years, scientists have learned that key beneficial infant gut bacteria Bifidobacterium infantis are disappearing from infants in high-resource areas such as the United States and Europe.

22 Dec 2025

Engineered extracellular vesicles enable antigen-specific regulatory T cell induction

A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University has developed a new class of engineered extracellular vesicles (EVs) capable of inducing antigen-specific regulatory T cells (Tregs), the immune cells that play a central role in suppressing excessive immune responses.

22 Dec 2025

Vibration-induced local vortices enable low-cost biomolecular condensate engineering

A research group led by Professor Hiroaki SUZUKI and Takeshi HAYAKAWA from the Faculty of Science and Engineering at Chuo University, graduate student Zhitai HUANG, graduate students Kanji KANEKO (at the time) and Ryotaro YONEYAMA (at the time), together with Specially Appointed Assistant Professor Tomoya MARUYAMA from the Research Center for Autonomous Systems Materialogy (ASMat), Institute of Integrated Research (IIR), Institute of Science Tokyo, and Professor Masahiro TAKINOUE from the Laboratory for Chemistry and Life Science, Institute of Integrated Research, Institute of Science Tokyo, has developed a novel and highly accessible technology for producing uniform Biomolecular Condensates using a simple, low-cost vibration platform.

22 Dec 2025

ARB drugs lead to better blood pressure treatment adherence

Patients who start their blood pressure treatment with ARB drugs continue with the same medicine to a greater extent than patients who start out with other drugs.

22 Dec 2025

Popular video games may offer meaningful emotional benefits for young adults

Women may derive greater long-term benefits from coronary artery bypass grafting compared with stents

Women with severe coronary heart disease causing narrowing or blockages in the arteries may derive greater long-term benefits from coronary artery bypass grafting compared with percutaneous coronary intervention, also known as stenting, according to a large study by Weill Cornell Medicine investigators.

22 Dec 2025

Homer1 gene plays a critical role in shaping attention

Attention disorders such as ADHD involve a breakdown in our ability to separate signal from noise. The brain is constantly bombarded with information, and focus depends on its ability to filter out distractions and detect what matters.

22 Dec 2025

Unlocking sleep-wake secrets with dual brain signal analysis

Understanding the dynamic neural mechanisms of sleep-wake cycles is a major challenge in sleep science and neuroengineering.

22 Dec 2025

Community awareness campaign helps improve early diagnosis of colorectal cancer in low-resource regions

In low-resource regions such as Nigeria, most people with colorectal cancer are diagnosed too late for curative treatment options.

22 Dec 2025

Splicing regulator U2AF1 promotes angiogenesis in cardiac injury

A study published in Engineering shows that a protein called U2 small nuclear RNA auxiliary factor 1 (U2AF1), released by immune cells known as macrophages, helps grow new blood vessels in the heart after a myocardial infarction (MI) by altering how the gene Yap1 is spliced.

22 Dec 2025

How family dynamics can have a profound impact on eating behavior

As the holiday season approaches, many families will gather around the dinner table, sharing meals and memories. But what if the way we eat during these gatherings is shaped by more than just tradition?

22 Dec 2025

Study charts the escalating spread of resistant bacteria and fungi

The success of modern medicine rests on the ability to control infections. But decades of antibiotic overuse—in hospitals, communities, and farms—have fueled a global surge in resistant microbes.

22 Dec 2025

Medicaid health plans step up outreach efforts ahead of GOP changes

Carmen Basu, bundled in a red jacket and woolly scarf, stood outside the headquarters of her local health plan one morning after picking up free groceries. She had brought her husband, teenage son, and 79-year-old mother-in-law to help.

22 Dec 2025

Getting a dog for the first time boosts walking and remote social ties

First-time dog owners in Japan showed significant increases in walking activity and non-face-to-face social contact over one year compared with non-dog owners. No significant changes were observed in vigorous activity or face-to-face social contact, highlighting specific behavioral associations rather than broad lifestyle shifts.

21 Dec 2025

Blood metabolite profiling outperforms BMI in predicting pregnancy complications

This study shows that a blood-based metabolomic signature linked to maternal BMI predicts gestational diabetes and preeclampsia more strongly than BMI alone, particularly in late pregnancy. A subset of 16 metabolites statistically mediates the BMI–gestational diabetes association, highlighting metabolic pathways that may improve prenatal risk stratification.

21 Dec 2025

Simple fruit granola intervention shows promising cardio-renal signals in CKD patients

A single-arm intervention study in Japanese adults with moderate chronic kidney disease found that replacing breakfast with fruit granola for two months lowered systolic blood pressure, reduced LDL-related lipid markers, and decreased a urinary marker of tubular injury. Renal function remained stable, bowel habits improved, and findings were exploratory due to the small, open-label design.

21 Dec 2025

Simple blood test maps hidden Alzheimer’s disease changes

This population-based study used plasma pTau217 to estimate how common Alzheimer’s disease neuropathological changes are across age and cognitive status in a Norwegian community cohort. Prevalence rose steeply with age and was strongly associated with APOE ε4 genotype, education level, and kidney function, with implications for future use of blood biomarkers in clinical practice.

21 Dec 2025

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Medical News

Rethinking Mendelian assumptions in inherited retinal degenerations

Remodeling the tumor microenvironment to unlock CAR-T cell potential

Early identification of nutrition risk in ICU patients using artificial intelligence

Probiotic supplementation restores beneficial gut bacteria in breastfed infants

Engineered extracellular vesicles enable antigen-specific regulatory T cell induction

Vibration-induced local vortices enable low-cost biomolecular condensate engineering

ARB drugs lead to better blood pressure treatment adherence

Popular video games may offer meaningful emotional benefits for young adults

Women may derive greater long-term benefits from coronary artery bypass grafting compared with stents

Homer1 gene plays a critical role in shaping attention

Unlocking sleep-wake secrets with dual brain signal analysis

Community awareness campaign helps improve early diagnosis of colorectal cancer in low-resource regions

Splicing regulator U2AF1 promotes angiogenesis in cardiac injury

How family dynamics can have a profound impact on eating behavior

Study charts the escalating spread of resistant bacteria and fungi

Medicaid health plans step up outreach efforts ahead of GOP changes

Getting a dog for the first time boosts walking and remote social ties

Blood metabolite profiling outperforms BMI in predicting pregnancy complications

Simple fruit granola intervention shows promising cardio-renal signals in CKD patients

Simple blood test maps hidden Alzheimer’s disease changes

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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