T Cell News and Research

Latest T Cell News and Research

Morphotek issued patent covering the use of chemical inhibitors of mismatch repair

Morphotek Inc. announced today the issuance of United States Patent 6,982,169 covering the use of chemical inhibitors to enhance evolution of target host cell genomes by reversibly regulating mismatch repair (MMR) in vivo.

23 Jan 2006

Scientists discover method to multiply an adult stem cell 30-fold

Adult stem cells may be free of the ethical concerns that hamper embryonic stem cell research, but they still pose formidable scientific challenges.

23 Jan 2006

Protein amplifies DNA injury signals - cues genetic repair mechanism to prevent tumors

A Mayo Clinic-led research collaboration has discovered that the protein MDC1 amplifies weak DNA injury signals so genetic repair can begin.

23 Jan 2006

SSRI antidepressants may also affect human immune system

Drugs that treat depression by manipulating the neurotransmitter serotonin in the brain may also affect the user's immune system in ways that are not yet understood, say scientists from Georgetown University Medical Center and a Canadian research institute.

23 Jan 2006

Ataxia gene identified

Researchers at the University of Minnesota Medical School have discovered the gene responsible for a type of ataxia, an incurable degenerative brain disease affecting movement and coordination.

23 Jan 2006

Histidine may be key to new therapies for cardiovascular disease

It's just one little amino acid, but it makes all the difference in protecting the heart from the harmful effects of heart attack and cardiac failure. Researchers from the University of Michigan Medical School suggest this amino acid, called histidine, could be the key to a new therapy for cardiovascular disease

23 Jan 2006

First genome-wide screen for protein complexes is completed

Researchers in Germany have finished the first complete analysis of the "molecular machines" in one of biology's most important model organisms: S. cerevisiae (baker's yeast). The study from the biotechnology company Cellzome, in collaboration with the European Molecular Biology Laboratory (EMBL), appears in this week's online edition of Nature.

23 Jan 2006

Palliative radiation cures some lung cancer patients

About one in a hundred patients with apparently incurable non-small cell lung cancer (NSCLC) survive five or more years after being given relatively small doses of radiation therapy (RT) meant to ease symptoms, according to a new study.

23 Jan 2006

Identification of Gli protein degradation signals that directly affect tumor latency

Dr. Anthony E. Oro and colleagues (Stanford University) have identified two key Gli protein degradation signals that directly affect tumor latency in a mouse model of human skin cancer.

22 Jan 2006

Novel compound stops brain cell degeneration in Alzheimer's disease

Drug discovery researchers at Northwestern University have developed a novel orally administered compound specifically targeted to suppress brain cell inflammation and neuron loss associated with Alzheimer's disease.

22 Jan 2006

Malaria parasite plasmodium shown to develop in lymph nodes

In the first quantitative, real-time imaging study of the travels of the malaria parasite Plasmodium through mammalian tissue, researchers at the Pasteur Institute in Paris found the parasites developing in an unexpected place: the lymph nodes.

22 Jan 2006

No link between mobile phones and brain tumours

In a four-year study, scientists at the Institute of Cancer Research in London and three British universities found no link between regular, long-term use of cell phones and glioma, the most common type of brain tumour.

22 Jan 2006

New findings about messenger molecule raise hopes for new drug

Uppsala University scientists have developed a new method for measuring the concentration of the messenger substance for cells, cyclic adenosine monophosphate (cAMP), in individual living cells.

18 Jan 2006

Compounds in blackcurrants could prevent Alzheimer's disease

Compounds in blackcurrants could prevent Alzheimer's disease and the characteristics of British berries suggest they do it best, writes Jennifer Rohn in Chemistry & Industry magazine.

18 Jan 2006

TCF21 gene shown to be a tumor suppressor

Researchers have identified a new and unusual tumor suppressor gene that may be important in cancers of the lung and head and neck. The study shows that restoring the inactivated gene can slow the growth of tumor cells.

18 Jan 2006

Mutated oncogene triggers aggressive breast cancer

Researchers at Dana-Farber Cancer Institute have identified a molecular interaction that triggers a particularly aggressive form of breast cancer, and suggest that attacking this target with selective drugs might improve treatment.

18 Jan 2006

Retinal degeneration - researchers advance understanding

Researchers have labored for decades to understand blindness-inducing neurodegenerative diseases such as age-related macular degeneration (AMD) and retinitis pigmentosa (RP).

18 Jan 2006

Bexarotene shows promise in cancer treatment.

Researchers at Washington University School of Medicine in St. Louis now report that a compound related to vitamin A shows promise in preventing or slowing tumor growth in mice prone to lung cancer. The compound, called bexarotene, doesn't cause the severe skin irritations that have limited the use of other vitamin A derivatives in cancer therapies.

18 Jan 2006

Researchers identify protein essential for the maintenance of synapses

Nerve cells store and transmit information via special contact sites called synapses. Synapses also play a role in determining what we remember and what we forget.

18 Jan 2006

Alzheimer's may be triggered by neuron division

A new study in mice suggests that Alzheimer's disease (AD) may be triggered when adult neurons try to divide. The finding helps researchers understand what goes wrong in the disease and may lead to new ways of treating it.

18 Jan 2006