Schizophrenia

Schizophrenia is a chronic debilitating disorder which affects more than two million Americans, and millions more worldwide. While significant progress has been made in understanding the disease and developing treatments, there remains a significant unmet medical need. More than 50% of patients switch their medication in a given year due to either poor response or the experience of adverse events.

Schizophrenia

Schizophrenia is a chronic mental health disorder that causes people to think, feel and perceive the world differently from the general population.

Schizophrenia Signs and Symptoms

Schizophrenia Diagnosis

Schizophrenia Prognosis

Schizophrenia Causes

Schizophrenia Mechanisms

Schizophrenia Interventions

Schizophrenia Neural Processes

Schizophrenia Medication

Schizophrenia Screening, Prevention and Management

Latest Schizophrenia News and Research

Single-cell analysis reveals gene disruptions in early-onset Alzheimer's brain regions

A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to reveal disruptions in gene function in three brain regions of patients with sporadic early onset Alzheimer's disease.

13 Jan 2026

Fruit fly study identifies genes regulating dopamine and sleep

Dopamine in the brain influences movement, learning, motivation and sleep. In humans, problems with dopamine are linked to conditions like Parkinson's disease, depression and sleep disorders.

13 Jan 2026

Researchers uncover unexpected role of the cerebellum in schizophrenia's negative symptoms

Apathy, social withdrawal, and loss of motivation — the so-called ''negative'' symptoms of schizophrenia — are among the most disabling and hardest to treat.

13 Jan 2026

New insights into how rhythmic brain waves create a coherent sense of bodily self

A new study from Karolinska Institutet, published in Nature Communications, reveals how rhythmic brain waves known as alpha oscillations help us distinguish between our own body and the external world.

12 Jan 2026

Study uncovers a neural brake that limits motivation during unpleasant situations

Most of us know the feeling: maybe it is making a difficult phone call, starting a report you fear will be criticized, or preparing a presentation that's stressful just to think about.

9 Jan 2026

Biodegradable pill improves medication adherence monitoring

In an advance that could help ensure people are taking their medication on schedule, MIT engineers have designed a pill that can report when it has been swallowed.

8 Jan 2026

Unveiling genetic links between schizophrenia and osteoporosis

A comprehensive genetic investigation led by Dr. Feng Liu at Tianjin Medical University General Hospital has uncovered striking molecular connections between schizophrenia and bone health, identifying 195 shared genetic loci that may explain why psychiatric patients face elevated fracture risks.

6 Jan 2026

TAAR1 mutation impairs brain signaling in schizophrenia

A genetic mutation passed from mother to children in families affected by schizophrenia has now been shown to completely silence a brain receptor that pharmaceutical companies are racing to target with new drugs.

6 Jan 2026

Gut microbes shown to directly shape brain function and evolution

A groundbreaking new study reveals that changes to the gut microbiome can change the way the brain works.

5 Jan 2026

Engineered sensor reveals the brain’s hidden chemical conversations

Scientists have engineered a protein able to record the incoming chemical signals of brain cells (as opposed to just their outgoing signals).

23 Dec 2025

Homer1 gene plays a critical role in shaping attention

Attention disorders such as ADHD involve a breakdown in our ability to separate signal from noise. The brain is constantly bombarded with information, and focus depends on its ability to filter out distractions and detect what matters.

22 Dec 2025

People with central vision loss can accurately judge approaching vehicles

People with central vision loss can judge the motion of vehicles almost as accurately as people with normal vision, a new international study shows.

19 Dec 2025

Neural mechanisms underlying behavioral flexibility revealed in mice

From work meetings to first dates, it's essential to adjust our behavior for success. In certain situations, it can even be a matter of life or death.

17 Dec 2025

Tau biology expands beyond microtubules to neurodegeneration, metabolism and mental illness

An Thought Leaders Invited Review published today in Genomic Psychiatry by Dr. Peng Lei and colleagues presents a sweeping synthesis of tau protein research that fundamentally reframes our understanding of this molecule's dual identity.

16 Dec 2025

Scientists discover rapid synapse adaptation in neuronal communication

Every movement you make and every memory you form depends on precise communication between neurons. When that communication is disrupted, the brain must rapidly rebalance its internal signaling to keep circuits functioning properly.

16 Dec 2025

Gut bacteria patterns differ in autism and siblings and link to social symptoms

This sibling-controlled East Asian study found that autistic individuals, their unaffected siblings, and typically developing controls differ in gut microbiota diversity and composition, with the clearest separation between autism and typical development. Specific taxa, particularly the butyrate-producing genus Anaerostipes, were modestly associated with social communication and internalising symptoms, supporting a gut–behaviour link without implying causality.

15 Dec 2025

Massive genetics study shows what truly separates and unites 14 psychiatric disorders

This large-scale genomic analysis of 14 psychiatric disorders shows that most heritable risk is shared across five broad genetic factors, with only limited disorder-specific variation. The study maps where risks converge or diverge biologically, revealing distinct cell type signatures and developmental pathways that may guide future diagnostic and therapeutic frameworks.

12 Dec 2025

Schizophrenia

Overview

Schizophrenia Signs and Symptoms

Schizophrenia Diagnosis

Schizophrenia Prognosis

Feature Articles

Schizophrenia Causes

Schizophrenia Mechanisms

Schizophrenia Interventions

Schizophrenia Neural Processes

Schizophrenia Medication

Schizophrenia Screening, Prevention and Management

Latest Schizophrenia News and Research

Single-cell analysis reveals gene disruptions in early-onset Alzheimer's brain regions

Fruit fly study identifies genes regulating dopamine and sleep

Researchers uncover unexpected role of the cerebellum in schizophrenia's negative symptoms

New insights into how rhythmic brain waves create a coherent sense of bodily self

Study uncovers a neural brake that limits motivation during unpleasant situations

Biodegradable pill improves medication adherence monitoring

Unveiling genetic links between schizophrenia and osteoporosis

TAAR1 mutation impairs brain signaling in schizophrenia

Gut microbes shown to directly shape brain function and evolution

Engineered sensor reveals the brain’s hidden chemical conversations

Homer1 gene plays a critical role in shaping attention

People with central vision loss can accurately judge approaching vehicles

Neural mechanisms underlying behavioral flexibility revealed in mice

Tau biology expands beyond microtubules to neurodegeneration, metabolism and mental illness

Scientists discover rapid synapse adaptation in neuronal communication

Gut bacteria patterns differ in autism and siblings and link to social symptoms

Massive genetics study shows what truly separates and unites 14 psychiatric disorders

Study reveals shared genetic roots across multiple psychiatric disorders

Researchers identify a distinct immuno-inflammatory biomarker across major psychiatric disorders

Shared genetic roots of 14 psychiatric disorders revealed

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Schizophrenia

Overview

Feature Articles

Schizophrenia Causes

Schizophrenia Mechanisms

Schizophrenia Interventions

Schizophrenia Neural Processes

Schizophrenia Medication

Schizophrenia Screening, Prevention and Management

Latest Schizophrenia News and Research

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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