Pharmacology News and Research

Latest Pharmacology News and Research

Study provides insights into functions of astrocytes following brain injury or disease

Astrocytes have long been implicated in the pathology of a range of human neurodegenerative diseases or injuries including Alzheimer's, Huntington's Parkinson's disease, brain trauma and spinal cord injury.

3 Feb 2017

‘Love hormone’ from insects could be used as drug lead to prevent uterine contractility in preterm labour

In a recent study published in "Scientific Reports", an international team of researchers led by MedUni Vienna report that an oxytocin-like neuropeptide ("inotocin") exhibited a specific pharmacological profile for the human receptors of oxytocin (known as the "love hormone") and vasopressin.

1 Feb 2017

New analysis reveals low incidence of liver cancer in patients with cirrhosis

Although one of the most serious complications of cirrhosis is liver cancer, or hepatocellular carcinoma (HCC), an analysis of health records revealed that the 10-year incidence of HCC in UK patients with cirrhosis is four percent or lower.

1 Feb 2017

Glucose deprivation in the brain triggers onset of cognitive decline, research shows

One of the earliest signs of Alzheimer's disease is a decline in glucose levels in the brain. It appears in the early stages of mild cognitive impairment -- before symptoms of memory problems begin to surface.

31 Jan 2017

Delays in availability of new treatments and incomprehensible price rises disadvantage cancer patients

Cancer patients are living longer and in many cases the disease is becoming chronic rather than acute. Access to drugs that help extend life and improve quality of life, and fair prices for those drugs are therefore essential for more and more people.

28 Jan 2017

LSD influences perception by stimulating serotonin receptors in the brain

Researchers from UZH have discovered how the perception of meaning changes in the brain under the influence of LSD. The serotonin 2A receptors are responsible for altered perception.

27 Jan 2017

Scientists discover new way to inhibit growth of glioblastoma

Scientists have found a way to inhibit the growth of glioblastoma, a type of brain cancer with low survival rates, by targeting a protein that drives growth of brain tumors, according to research from the Peter O'Donnell Jr. Brain Institute and Harold C. Simmons Comprehensive Cancer Center.

25 Jan 2017

Cervicovaginal microbial communities in pregnant woman may be key to preventing preterm birth

A team of researchers that has confirmed the presence of bacteria in a woman's vagina and cervix may either increase the risk of premature birth or have a protective effect against it, has won the March of Dimes Award for Best Abstract on Prematurity at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting. The findings will be presented Thursday, January 26, at 1:15 p.m. PST at Caesars Palace Augustus Ballroom in Las Vegas.

24 Jan 2017

Researchers uncover mechanism of resistance used by triple negative breast cancer

Breast cancer cells are evasive, finding ways to bypass drugs designed to stop their unchecked growth.

20 Jan 2017

Pre-operative enteral nutrition linked to reduced rates of complications after Crohn's disease surgery

Despite improvements in medical care, about two-thirds of patients with Crohn's disease develop complications requiring intestinal surgery at some time, and post-operative healing can be complicated.

20 Jan 2017

Exposure to insecticides that mimic melatonin could put people at higher risk for diabetes

Synthetic chemicals commonly found in insecticides and garden products bind to the receptors that govern our biological clocks, University at Buffalo researchers have found.

19 Jan 2017

Study shows structural impact of membrane lipids on medically relevant serotonin transporters

Neurotransmitter transporters are some of the most popular transport proteins in research as they play a major role in the processing of signals in the brain. A joint study by TU Wien and the Medical University of Vienna has now successfully demonstrated for the first time the structural impact of membrane lipids on medically relevant serotonin transporters.

19 Jan 2017

Researchers uncover how stress hormone prevents digestive enzymes from damaging pancreas

UT Southwestern Medical Center researchers have uncovered the mechanism by which the stress hormone FGF21 keeps digestive enzymes from damaging the pancreas.

18 Jan 2017

Researchers identify brain cell types from cell culture of adult human neurons

Studying brain disorders in people and developing drugs to treat them has been slowed by the inability to investigate single living cells from adult patients

18 Jan 2017

Blocking molecular signaling pathway could prevent or reverse peripheral neuropathy

Researchers at University of California San Diego School of Medicine, with colleagues at the National Institute of Diabetes and Digestive and Kidney Diseases, the University of Manitoba and St. Boniface Hospital Albrechtsen Research Centre in Canada, have identified a molecular signaling pathway that, when blocked, promotes sensory neuron growth and prevents or reverses peripheral neuropathy in cell and rodent models of type 1 and 2 diabetes, chemotherapy-induced neuropathy and HIV.

18 Jan 2017

Penn State researchers develop novel compound to combat cytomegalovirus

A Retro94-based compound may prevent a common and sometimes fatal virus -- human cytomegalovirus (CMV) -- from reproducing and help to protect immunocompromised patients, such as those with HIV, on chemotherapy, with transplants, and infants from the effects of the disease, according to Penn State College of Medicine researchers.

10 Jan 2017

Mediterranean plants may become source for 'elixir of life'

The Mediterranean is a haven for lovers of crystal-clear seas and sun-kissed landscapes. Now, thanks to the work of scientists from the University of Malta and the Centre National de la Recherche Scientifique, it has the added appeal of being an actual fountain of youth.

9 Jan 2017

Scientists develop new technique to control proteins inside live cells with light

Proteins are the workhorse molecules of life. Among their many jobs, they carry oxygen, build tissue, copy DNA for the next generation, and coordinate events within and between cells.

6 Jan 2017

Second-hand smoke exposures before conception affect fetal brain development

Exposure to second-hand tobacco smoke -- even before conception -- appears to have a lingering impact that can later impair the brain development of a fetus, researchers at Duke Health report.

5 Jan 2017

Study links acid suppression therapy to increased risk of intestinal infections

In a population-based study from Scotland, use of commonly-prescribed acid suppression medications such as proton pump inhibitors (PPIs) was linked with an increased risk of intestinal infections with C. difficile and Campylobacter bacteria, which can cause considerable illness.

5 Jan 2017

Pharmacology News and Research

Latest Pharmacology News and Research

Study provides insights into functions of astrocytes following brain injury or disease

‘Love hormone’ from insects could be used as drug lead to prevent uterine contractility in preterm labour

New analysis reveals low incidence of liver cancer in patients with cirrhosis

Glucose deprivation in the brain triggers onset of cognitive decline, research shows

Delays in availability of new treatments and incomprehensible price rises disadvantage cancer patients

LSD influences perception by stimulating serotonin receptors in the brain

Scientists discover new way to inhibit growth of glioblastoma

Cervicovaginal microbial communities in pregnant woman may be key to preventing preterm birth

Researchers uncover mechanism of resistance used by triple negative breast cancer

Pre-operative enteral nutrition linked to reduced rates of complications after Crohn's disease surgery

Exposure to insecticides that mimic melatonin could put people at higher risk for diabetes

Study shows structural impact of membrane lipids on medically relevant serotonin transporters

Researchers uncover how stress hormone prevents digestive enzymes from damaging pancreas

Researchers identify brain cell types from cell culture of adult human neurons

Blocking molecular signaling pathway could prevent or reverse peripheral neuropathy

Penn State researchers develop novel compound to combat cytomegalovirus

Mediterranean plants may become source for 'elixir of life'

Scientists develop new technique to control proteins inside live cells with light

Second-hand smoke exposures before conception affect fetal brain development

Study links acid suppression therapy to increased risk of intestinal infections

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Pharmacology News and Research

Latest Pharmacology News and Research

Industry Focus - Biopharma eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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