Gene News and Research

Latest Gene News and Research

Vitamin A derivative suppresses immune response and cancer vaccine efficacy

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A-all-trans retinoic acid-compromises both the body's normal anti-cancer immune response and, in a different context, the efficacy of a promising type of cancer vaccine.

5 Jan 2026

Jumping genes reshape cancer genomes through 3D chromatin interactions

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.

5 Jan 2026

Gut microbes shown to directly shape brain function and evolution

A groundbreaking new study reveals that changes to the gut microbiome can change the way the brain works.

5 Jan 2026

RNA splicing and processing genes emerge as central drivers of aging across tissues

A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled "A combination of differential expression and network connectivity analyses identifies a common set of RNA splicing and processing genes altered with age across human tissues."

5 Jan 2026

Researchers identify hundreds of genes essential for the development of brain cells

An international research team identified hundreds of genes essential for the development of brain cells, including one gene linked to a severe neurodevelopmental disorder not previously described.

5 Jan 2026

Two bacterial shutdown modes explain antibiotic persistence and relapse

New study reveals that bacteria can survive antibiotic treatment through two fundamentally different "shutdown modes," not just the classic idea of dormancy.

4 Jan 2026

New method can help better assess precision genome editing technology

Scientists and physicians can better assess precision genome editing technology using a new method made public today by St. Jude Children's Research Hospital. Significant amounts of time and resources spent improving CRISPR gene editing technology focus on identifying small off-target sites that pose a safety risk, which is also technically challenging.

2 Jan 2026

A mathematical solution for precise control of cellular “noise”

Why does cancer sometimes recur after chemotherapy? Why do some bacteria survive antibiotic treatment? In many cases, the answer appears to lie not in genetic differences, but in biological noise - random fluctuations in molecular activity that occur even among genetically identical cells.

2 Jan 2026

Newly identified rare genetic variant reduces the risk of leukemia

A newly identified and rare genetic variant slows the growth of mutated blood stem cells, researchers report, and it reduces the risk of leukemia.

2 Jan 2026

How modern diets are driving rapid evolution in gut bacteria

A novel iLDS statistic uncovers adaptive gene sweeps in gut bacteria, highlighting evolutionary responses to modern diets and enhancing microbiome studies.

2 Jan 2026

Study uncovers how aggressive breast cancer cells escape immune defenses

With a new study in the journal Science Bulletin, researchers at Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University have discovered a new way that aggressive breast cancer cells escape the immune defenses.

1 Jan 2026

Plasmid-borne resistance drives global expansion of dangerous Klebsiella strains

A recent study published in Engineering has shed light on the transmission and epidemiological trends of tmexCD1-toprJ1-positive Klebsiella pneumoniae across various ecological niches, highlighting the potential threat this antibiotic-resistant bacterium poses to global public health.

31 Dec 2025

Viruses on plastic waste pose new antibiotic resistance risks

Plastic pollution does more than litter landscapes and oceans. According to a new perspective article published in Biocontaminant, viruses living on plastic surfaces may play an underrecognized role in spreading antibiotic resistance, raising concerns for environmental and public health worldwide.

31 Dec 2025

New computational method reconstructs how cells decide their fate

Researchers from Kyushu University have developed an innovative computational method, called ddHodge, that can reconstruct the complex dynamics of how cells decide their fate.

30 Dec 2025

Silica nanomatrix enhances immunotherapy for solid tumors

Cancer has long remained a leading cause of death worldwide and in Hong Kong, accounting for 30% of all disease-related deaths in the city in 2025. While chemotherapy remains a major treatment modality, its side effects and the risk of relapse challenges for patients.

30 Dec 2025

Epigenetic clocks accurately predict age from human skeletal muscle

A new research paper was published in Volume 17, Issue 11 of Aging-US on November 26, 2025, titled "Epigenetic aging signatures and age prediction in human skeletal muscle."

30 Dec 2025

Dihydrotanshinone I induces autophagic cell death in ovarian cancer

A recent study published in Engineering has shed light on the potential therapeutic effects of dihydrotanshinone I (DHT), a compound derived from the traditional Chinese herb Salvia miltiorrhiza, on ovarian cancer.

30 Dec 2025

Imaging-enhanced knowledge graphs reveal new targets for heart disease treatment

Knowledge graphs are a powerful tool for bringing together information from biological databases and linking what is already known about genes, diseases, treatments, molecular pathways and symptoms in a structured network.

30 Dec 2025

Minimal residual disease monitoring can transform breast cancer care

Despite major therapeutic advances, breast cancer remains prone to recurrence, particularly in patients with early-stage disease who appear disease-free after treatment.

30 Dec 2025

Epigenetic plasticity in germinal center B cells may help explain lymphoma origins

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During their preparation for this battle, B cells transiently revert to a more flexible, or plastic, stem-cell-like state in the lymph nodes, according to a new preclinical study from Weill Cornell Medicine investigators.

30 Dec 2025

Gene News and Research

Latest Gene News and Research

Vitamin A derivative suppresses immune response and cancer vaccine efficacy

Jumping genes reshape cancer genomes through 3D chromatin interactions

Gut microbes shown to directly shape brain function and evolution

RNA splicing and processing genes emerge as central drivers of aging across tissues

Researchers identify hundreds of genes essential for the development of brain cells

Two bacterial shutdown modes explain antibiotic persistence and relapse

New method can help better assess precision genome editing technology

A mathematical solution for precise control of cellular “noise”

Newly identified rare genetic variant reduces the risk of leukemia

How modern diets are driving rapid evolution in gut bacteria

Study uncovers how aggressive breast cancer cells escape immune defenses

Plasmid-borne resistance drives global expansion of dangerous Klebsiella strains

Viruses on plastic waste pose new antibiotic resistance risks

New computational method reconstructs how cells decide their fate

Silica nanomatrix enhances immunotherapy for solid tumors

Epigenetic clocks accurately predict age from human skeletal muscle

Dihydrotanshinone I induces autophagic cell death in ovarian cancer

Imaging-enhanced knowledge graphs reveal new targets for heart disease treatment

Minimal residual disease monitoring can transform breast cancer care

Epigenetic plasticity in germinal center B cells may help explain lymphoma origins

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

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