Colorectal Cancer

Colorectal Cancer is cancer that develops in the colon (the longest part of the large intestine) and/or the rectum (the last several inches of the large intestine before the anus). In the United States, it is the fourth most common cancer in men and women. Caught early, it is often curable.

What Causes Colorectal Cancer?

Cancer occurs when a normal cell divides and multiples uncontrollably. Normally cells are regulated in their growth, maturity, division and death by the DNA present in their nucleus. With damage to the DNA the cells may become rogue and multiply uncontrollably to give rise to tumors.

Colorectal Cancer Symptoms

Colorectal Cancer and Organ Preservation

Colorectal Cancer Prevention

Colorectal Cancer Pathogenesis

What is Colorectal Cancer?

Colorectal Cancer Diagnosis

Colorectal Cancer Management

Colorectal Cancer Prognosis

Microbial Dysbiosis and Colorectal Cancer

Latest Colorectal Cancer News and Research

Novel liquid biopsy technology could advance cancer diagnostics and monitoring

A novel liquid biopsy technology is set to advance cancer diagnostics and monitoring by overcoming the long-standing challenge of simultaneously achieving high sensitivity, broad coverage, and simple workflow.

14 Jan 2026

Bacterial toxin shrinks tumors, enhances immune response in colorectal cancer study

A toxin secreted by cholera bacteria can inhibit the growth of colorectal cancer without causing any measurable damage to the body. This is shown by a new study by researchers at Umeå University, Sweden.

14 Jan 2026

Common food preservatives may raise cancer risk

Higher intake of certain food preservatives is associated with increased cancer rates, particularly breast and prostate cancers, highlighting safety concerns.

13 Jan 2026

DNA analysis of colorectal polyps improves diagnosis and treatment

In about 5–10% of colorectal cancer patients, hereditary factors play a role, with higher percentages among younger patients.

12 Jan 2026

New research decodes the bacterial “zip code” of colorectal cancer for prediction and survival

Bacterial communities in colorectal cancer reveal patterns linked to tumor genetics and patient outcomes, paving the way for personalized treatment strategies.

From BGI Genomics 9 Jan 2026

New federal guidelines shift cervical cancer screening to HPV testing

New cervical cancer screening guidelines emphasize self-collection and hrHPV testing, aiming to increase screening rates and improve women's health outcomes.

8 Jan 2026

Enveda’s third asset to the clinic with US FDA IND clearance: What it means for Inflammatory Bowel Disease

Enveda, a multi-asset clinical-stage biotech company pioneering the discovery and development of a new generation of small-molecule drugs derived from life’s chemistry, has announced that the US Food and Drug Administration (FDA) has cleared the Company’s Investigational New Drug (IND) application for ENV-6946.

From Hanson Wade Group - 4th Precision Medicine in Inflammatory Bowel Disease Summit 6 Jan 2026

AI language models actually help in digestive disease care

Large language models could transform digestive disorder management, but further RCTs are essential to validate their effectiveness and safety in healthcare.

6 Jan 2026

CT-based quantification of tumor fibrosis guides chemotherapy in pancreatic cancer

On October 3, 2025, a multicenter team from Shenzhen University, Xiangya Hospital of Central South University, Zhujiang Hospital of Southern Medical University, Wuxi People's Hospital Affiliated to Nanjing Medical University, among others jointly reported a novel noninvasive method for quantifying tumor fibrosis based on preoperative enhanced CT.

23 Dec 2025

Community awareness campaign helps improve early diagnosis of colorectal cancer in low-resource regions

In low-resource regions such as Nigeria, most people with colorectal cancer are diagnosed too late for curative treatment options.

22 Dec 2025

Opposing protein forces fine tune mRNA stability in human cells

A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and disorders - including cancers, neurodegenerative diseases and immune disorders - originate, as well as how to potentially treat them, according to researchers at Penn State.

16 Dec 2025

Frog-derived bacteria offer dual-action anticancer effects and high safety

A research team of Prof. Eijiro Miyako at the Japan Advanced Institute of Science and Technology (JAIST) has discovered that the bacterium Ewingella americana, isolated from the intestines of Japanese tree frogs (Dryophytes japonicus), possesses remarkably potent anticancer activity. This groundbreaking research has been published in the international journal Gut Microbes.

16 Dec 2025

Blood test identifies colon cancer patients who benefit from anti-inflammatory medication

A blood test could help doctors decide which patients with colon cancer should receive anti-inflammatory medication along with chemotherapy after surgery, according to new study in JAMA Oncology.

15 Dec 2025

New insights explain the Treg paradox in colorectal cancer

In most solid tumors, high numbers of regulatory T (Treg) cells are associated with poorer outcomes because they dampen the immune system's ability to fight against a tumor.

15 Dec 2025

New CDC grant supports expansion of colorectal cancer screening across rural Pennsylvania

Increasing colorectal cancer screening rates among communities with the greatest need is the goal of a five-year, $4.2 million grant from the Centers for Disease Control and Prevention (CDC) to Penn State College of Medicine.

11 Dec 2025

Researchers discover the enzyme responsible for chromothripsis in cancer

University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which a single chromosome is shattered into pieces and rearranged in a scrambled order, allowing cancer cells to rapidly evolve and become resistant to treatment.

11 Dec 2025

Integrating AI into colon cancer diagnosis improves the speed and accuracy of detection

A recent study reveals that integrating Artificial Intelligence (AI) into colon cancer diagnosis over the past five years has significantly improved the speed and accuracy of the detection of the deadly disease.

8 Dec 2025

Study reveals unequal burden of sudden cardiac death among colorectal cancer survivors

A new research paper was published in Volume 12 of Oncoscience on November 7, 2025, titled "Temporal trends and disparities in sudden cardiac death among colorectal cancer patients: A nationwide study."

4 Dec 2025

AR3-based optogenetic strategy shows high efficacy in inducing apoptosis and antitumor effects

One of the hallmarks of cancer cells is their ability to evade apoptosis, or programmed cell death, through changes in protein expression.

2 Dec 2025

Generative AI aids discovery of ISM3830's novel scaffold

Casitas B-lineage lymphoma-b (CBLB) is an E3 ubiquitin–protein ligase that functions as an intracellular checkpoint and master negative regulator of T‑cell and natural killer (NK) cell activation, playing a central role in modulating T-cell activation and immune tolerance, and its inhibition enhances T cells and NK cells function, also provides a strategy for the function restoration of exhausted T cells.

1 Dec 2025

Colorectal Cancer

Overview

Colorectal Cancer Symptoms

Colorectal Cancer and Organ Preservation

Colorectal Cancer Prevention

Feature Articles

Colorectal Cancer Pathogenesis

What is Colorectal Cancer?

Colorectal Cancer Diagnosis

Colorectal Cancer Management

Colorectal Cancer Prognosis

Microbial Dysbiosis and Colorectal Cancer

Latest Colorectal Cancer News and Research

Novel liquid biopsy technology could advance cancer diagnostics and monitoring

Bacterial toxin shrinks tumors, enhances immune response in colorectal cancer study

Common food preservatives may raise cancer risk

DNA analysis of colorectal polyps improves diagnosis and treatment

New research decodes the bacterial “zip code” of colorectal cancer for prediction and survival

New federal guidelines shift cervical cancer screening to HPV testing

Enveda’s third asset to the clinic with US FDA IND clearance: What it means for Inflammatory Bowel Disease

AI language models actually help in digestive disease care

CT-based quantification of tumor fibrosis guides chemotherapy in pancreatic cancer

Community awareness campaign helps improve early diagnosis of colorectal cancer in low-resource regions

Opposing protein forces fine tune mRNA stability in human cells

Frog-derived bacteria offer dual-action anticancer effects and high safety

Blood test identifies colon cancer patients who benefit from anti-inflammatory medication

New insights explain the Treg paradox in colorectal cancer

New CDC grant supports expansion of colorectal cancer screening across rural Pennsylvania

Researchers discover the enzyme responsible for chromothripsis in cancer

Integrating AI into colon cancer diagnosis improves the speed and accuracy of detection

Study reveals unequal burden of sudden cardiac death among colorectal cancer survivors

AR3-based optogenetic strategy shows high efficacy in inducing apoptosis and antitumor effects

Generative AI aids discovery of ISM3830's novel scaffold

Industry Focus eBook - Oncology (1st Edition) eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Colorectal Cancer

Overview

Feature Articles

Colorectal Cancer Pathogenesis

What is Colorectal Cancer?

Colorectal Cancer Diagnosis

Colorectal Cancer Management

Colorectal Cancer Prognosis

Microbial Dysbiosis and Colorectal Cancer

Latest Colorectal Cancer News and Research

Industry Focus eBook - Oncology (1st Edition) eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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