Chromosome News and Research

Latest Chromosome News and Research

Researchers develop new technique to create naïve pluripotent stem cells

Scientists at the University of Cambridge have for the first time shown that it is possible to derive from a human embryo so-called 'naïve' pluripotent stem cells - one of the most flexible types of stem cell, which can develop into all human tissue other than the placenta.

7 Mar 2016

Discovery could lead to better therapies for people with obsessive compulsive disorder

Research led by investigators in veterinary and human medicine has identified genetic pathways that exacerbate severity of canine compulsive disorder in Doberman pinschers, a discovery that could lead to better therapies for obsessive compulsive disorder in people.

27 Feb 2016

Clinical validation study on MaterniT GENOME test published in American Journal of Obstetrics and Gynecology

Sequenom, Inc., a life sciences company committed to enabling healthier lives through the development of innovative products and services, today announced the publication of a clinical validation study on the MaterniT GENOME laboratory-developed test in the American Journal of Obstetrics and Gynecology.

26 Feb 2016

New anti-ageing therapy may be effective against aplastic anaemia

Aplastic anaemia is a rare, and potentially fatal, disease of the blood, by which the bone marrow is unable to generate blood cells at the appropriate pace. Many forms of aplastic anaemia share an important link with the ageing process: the shortening of telomeres, structures that protect the ends of chromosomes.

25 Feb 2016

Researchers analyze how Topo II enzyme may affect stability of genomes

While researchers are now familiar with how cancer begins—cells mutate and then multiply wildly out of control—it is still uncertain exactly how that mutation starts in the molecules of the cells.

22 Feb 2016

African Americans with common genetic variants at increased risk for blood clots

New research published online today in Blood, the Journal of the American Society of Hematology (ASH), identifies common genetic variants predominantly found in African Americans that double their risk for blood clots.

18 Feb 2016

Study reveals link between genomic instability, aneuploidy and cancer

A recent analysis of 43,205 human tumours unveiled that 68% of solid tumours are aneuploid, that is to say, they have an altered number of chromosomes. In recent years, scientists have attempted to clarify whether this aneuploidy contributes to tumour development or whether it is a co-lateral effect of the genomic instability of cancer cells, which increase the rate of mutations and the likelihood of cancer.

9 Feb 2016

New technique allows better understanding of cellular stress reaction

Stress in the body's cells is both the cause and consequence of inflammatory diseases or cancer. The cells react to stress to protect themselves. Researchers at the University of Zurich have now developed a new technique that allows studying a fundamental response to stress in much more detail than previously possible: the ADP-ribosylation of chromatin.

9 Feb 2016

Abnormal breakage of chromosomes in white blood cells triggers aggressive form of ALL

A research team led by St. Jude Children's Research Hospital scientists has discovered details of how the abnormal breakage and rearrangement of chromosomes in white blood cells triggers a particularly aggressive form of acute lymphoblastic leukemia (ALL). Such leukemias are cancers of white blood cells, in which genetic mutations trigger overproduction of immature cells, called lymphoblasts.

9 Feb 2016

Aggression influences new nerve cell production in the brain

A group of neurobiologists from Russia and the USA, including Dmitry Smagin, Tatyana Michurina, and Grigori Enikolopov from Moscow Institute of Physics and Technology, have proven experimentally that aggression has an influence on the production of new nerve cells in the brain.

8 Feb 2016

LouLou Foundation, Penn Med set up Program of Excellence to develop treatments for children with CDKL5

The London-based LouLou Foundation and the Orphan Disease Center of the Perelman School of Medicine at the University of Pennsylvania have established a Program of Excellence to develop effective treatments for children with CDKL5, a rare X-chromosome-linked genetic disorder that causes severe neuro-developmental impairment and early-onset, difficult-to-control seizures.

8 Feb 2016

Study sheds light on mechanisms linked to formation of healthy egg cells in humans

Congenital disorders such as Down's syndrome could be better understood, following new insights into how healthy cells are formed.

3 Feb 2016

Researchers identify new targets that may help prevent and cure colon cancer

When the audio on your television set or smart phone is too loud, you simply turn down the volume. What if we could do the same for the signaling in our bodies that essentially causes normal cells to turn cancerous? New discoveries by researchers at the Stephenson Cancer Center at the University of Oklahoma may point to new ways to do just that.

3 Feb 2016

New gene cut-and-paste methods help correct disease-causing mutation in animal model

For the first time, researchers have treated an animal model of a genetic disorder using a viral vector to deliver genome-editing components in which the disease- causing mutation has been corrected.

3 Feb 2016

Two studies shed new light on nature of tandem DNA repeat arrays

A pair of studies by a team of scientists has shed new light on the nature of a particular type of DNA sequences—tandem DNA repeat arrays—that play important roles in transcription control, genome organization, and development.

29 Jan 2016

Researchers find how microtubules, motor proteins assemble into macroscopic networks

What bones are to bodies, the cytoskeleton is to cells. The cytoskeleton maintains cellular structure, builds appendages like flagella and, together with motor proteins, powers cellular movement, transport, and division. Microtubules are a critical component of the cytoskeleton, vital for cell division and, because of that, an excellent target for chemotherapy drugs.

29 Jan 2016

Using centrifugal elutriation and flow cytometry to answer biological questions: an interview with Peter Lopez

Flow Cytometry, the measurement of various cellular characteristics as they flow through a measuring apparatus, has so many applications.

From Beckman Coulter Life Sciences - Centrifugation 27 Jan 2016

UAB discovery may offer new therapeutic approaches to asthma

University of Alabama at Birmingham researchers have found a previously unknown step in the pathway that leads to asthma, a discovery that may offer new therapeutic approaches to this incurable disease. Asthma affects more than 25 million people in the United States, including about 7 million children.

27 Jan 2016

Scientists find how APOBEC protein becomes dangerous when DNA replication process goes wrong

Cancer is caused by the growth of an abnormal cell which harbours DNA mutations, "copy errors" occurring during the DNA replication process. If these errors do take place quite regularly without having any damaging effect on the organism, some of them affect a specific part of the genome and cause the proliferation of the mutant cell, which then invades the organism.

25 Jan 2016

Study provides evidence for use of inherited genetic markers to improve melanoma prognostication

Melanoma is the most dangerous and lethal form of skin cancer. But just how long will a patient survive following the removal of a melanoma tumor? A more definitive answer to that question could come from new studies at NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center. Researchers there have discovered an inherited genetic marker that might provide clinicians with a personalized tool to gauge an individual's survival and determine which patients require closer monitoring in the years following surgery.

21 Jan 2016

Chromosome News and Research

Latest Chromosome News and Research

Researchers develop new technique to create naïve pluripotent stem cells

Discovery could lead to better therapies for people with obsessive compulsive disorder

Clinical validation study on MaterniT GENOME test published in American Journal of Obstetrics and Gynecology

New anti-ageing therapy may be effective against aplastic anaemia

Researchers analyze how Topo II enzyme may affect stability of genomes

African Americans with common genetic variants at increased risk for blood clots

Study reveals link between genomic instability, aneuploidy and cancer

New technique allows better understanding of cellular stress reaction

Abnormal breakage of chromosomes in white blood cells triggers aggressive form of ALL

Aggression influences new nerve cell production in the brain

LouLou Foundation, Penn Med set up Program of Excellence to develop treatments for children with CDKL5

Study sheds light on mechanisms linked to formation of healthy egg cells in humans

Researchers identify new targets that may help prevent and cure colon cancer

New gene cut-and-paste methods help correct disease-causing mutation in animal model

Two studies shed new light on nature of tandem DNA repeat arrays

Researchers find how microtubules, motor proteins assemble into macroscopic networks

Using centrifugal elutriation and flow cytometry to answer biological questions: an interview with Peter Lopez

UAB discovery may offer new therapeutic approaches to asthma

Scientists find how APOBEC protein becomes dangerous when DNA replication process goes wrong

Study provides evidence for use of inherited genetic markers to improve melanoma prognostication

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Chromosome News and Research

Latest Chromosome News and Research

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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