Chemotherapy News and Research

Latest Chemotherapy News and Research

Scientists identify key molecules that mediate radioresistance in aggressive brain cancer

Scientists have identified key molecules that mediate radioresistance in glioblastoma multiforme; these molecules are a potential target for the treatment of this brain cancer.

30 Sep 2020

Cancer chemotherapy changes the function of cells that repair heart injury

Cancer chemotherapy changes the function of cells that repair heart injury, researchers at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) discovered.

30 Sep 2020

Study shows how Cisplatin chemotherapy leads to neuronal apoptosis

Despite the great advances in cancer research in recent years, treatments that can cause very severe adverse effects are still used. This is the case of neuropathy caused by chemotherapy with platinum derivatives, such as Cisplatin and Oxaliplatin.

30 Sep 2020

Antibody improves progression-free survival in patients with advanced prostate cancer

An antibody for treating advanced prostate cancer improves progression-free survival in patients with metastasised, castration-resistant prostate cancer.

29 Sep 2020

Phase 1 trial of new class of drugs shows promise in range of advanced cancers

A new precision drug which stops cancer from repairing its DNA has shown promise in an early-stage clinical trial - highlighting the potential of a new class of drugs known as ATR inhibitors.

29 Sep 2020

COVID-19-related interruptions in rehabilitation care causes emotional distress in breast cancer survivors

Beyond the tragic surges in hospitalizations and deaths, the first months of the COVID-19 pandemic disrupted healthcare for people with a wide range of medical conditions - including cancer.

29 Sep 2020

Genetic testing is cost-effective, beneficial for newly diagnosed patients with metastatic GIST

Because gastrointestinal stromal tumors (GIST) are sensitive to the targeted small molecule therapy imatinib, oncologists tend to treat all patients with metastatic GIST with this drug. However, because this rare type of cancer is caused by different genetic mutations, imatinib does not help all patients equally.

28 Sep 2020

Scientists identify a new way to regulate cell plasticity

Cell plasticity is a property by which a cell can take on different and reversible identities. Cell plasticity is also essential for embryo development and for the correct function of the immune system.

28 Sep 2020

Targeted therapy found to be effective at shrinking tumors in patients with nonsmall-cell lung cancer

An international team of researchers has found that selpercatinib, a drug that precisely targets cancers driven by mutations or alterations in the gene RET, was effective at shrinking tumours in patients with nonsmall cell lung cancer (NSCLC), with a majority of patients living for more than a year without disease progression.

28 Sep 2020

Study identifies hiding place where tumor cells shelter from chemotherapy in childhood leukemia

The stroma of the choroid plexus is one of the locations within the central nervous system (CNS) that serves as a shelter for tumor cells, allowing them to elude chemotherapy and potentially cause subsequent relapses in childhood acute lymphoblastic leukaemia, according to research led by the Complutense University of Madrid.

25 Sep 2020

Researchers develop a stable nano-carrier for medications

Medications often have unwanted side-effects. One reason is that they reach not only the unhealthy cells for which they are intended, but also reach and have an impact on healthy cells.

25 Sep 2020

Researchers use natural pigment for screening cell viability

Synthetic dyes are commonly used to assess the toxicity of chemical compounds in cell cultures. However, these dyes damage cells, rendering the cultures useless for long-term experiments.

25 Sep 2020

Biomarker candidates could aid in earlier diagnosis of mesothelioma

Mesothelioma is a deadly cancer mainly caused by exposure to asbestos fibers. Unfortunately, mesothelioma is generally diagnosed at an already advanced stage and none of the therapeutic strategies tried so far is able to eradicate the disease.

24 Sep 2020

Researchers develop 'Trojan horse' approach to destroy cancer cells

Cancer cells are killed in lab experiments and tumour growth reduced in mice, using a new approach that turns a nanoparticle into a 'Trojan horse' that causes cancer cells to self-destruct, a research team at the Nanyang Technological University, Singapore (NTU Singapore) has found.

23 Sep 2020

New T-cell-based vaccine strategy provides broader protection against seasonal influenza

As Americans begin pulling up their sleeves for an annual flu vaccine, researchers at the University of Wisconsin-Madison have provided new insights into an alternative vaccine approach that provides broader protection against seasonal influenza.

23 Sep 2020

Researchers identify genetic markers linked to higher risk of capecitabine-induced hand-foot syndrome

Capecitabine is a chemotherapy drug used for breast and colorectal Cancer cancer. It can extend survival rate by nearly 10%.

21 Sep 2020

Immunotherapy benefits patients with gastric and esophageal cancers, new data shows

New data presented at ESMO 2020 have shown that immunotherapy is beneficial for patients with gastric and esophageal cancers who currently have poor survival.

21 Sep 2020

PROfound phase III results offer new targeted treatment for metastatic prostate cancer

Results from the PROfound phase III study, funded by AstraZeneca and Merck Sharp & Dohme, open up a much-needed new treatment avenue for the more precise and effective treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) whose disease has progressed with hormonal therapy.

21 Sep 2020

Post-operative radiotherapy in NSCLC shows no statistically difference in 3-year disease-free survival

Post-operative radiotherapy (PORT) used in patients with non-small-cell lung cancer (NSCLC) following complete resection and after (neo) adjuvant chemotherapy shows no statistically significant difference in 3-year disease-free survival (DFS), according to data presented at ESMO 2020.

21 Sep 2020

KRASG12C inhibitor sotorasib shows durable clinical benefits for solid cancers

In a Phase I clinical trial for patients with advanced solid cancers marked by KRAS G12C mutations, the KRASG12C inhibitor sotorasib (AMG 510) resulted in manageable toxicities and durable clinical benefits.

21 Sep 2020

Chemotherapy News and Research

Latest Chemotherapy News and Research

Scientists identify key molecules that mediate radioresistance in aggressive brain cancer

Cancer chemotherapy changes the function of cells that repair heart injury

Study shows how Cisplatin chemotherapy leads to neuronal apoptosis

Antibody improves progression-free survival in patients with advanced prostate cancer

Phase 1 trial of new class of drugs shows promise in range of advanced cancers

COVID-19-related interruptions in rehabilitation care causes emotional distress in breast cancer survivors

Genetic testing is cost-effective, beneficial for newly diagnosed patients with metastatic GIST

Scientists identify a new way to regulate cell plasticity

Targeted therapy found to be effective at shrinking tumors in patients with nonsmall-cell lung cancer

Study identifies hiding place where tumor cells shelter from chemotherapy in childhood leukemia

Researchers develop a stable nano-carrier for medications

Researchers use natural pigment for screening cell viability

Biomarker candidates could aid in earlier diagnosis of mesothelioma

Researchers develop 'Trojan horse' approach to destroy cancer cells

New T-cell-based vaccine strategy provides broader protection against seasonal influenza

Researchers identify genetic markers linked to higher risk of capecitabine-induced hand-foot syndrome

Immunotherapy benefits patients with gastric and esophageal cancers, new data shows

PROfound phase III results offer new targeted treatment for metastatic prostate cancer

Post-operative radiotherapy in NSCLC shows no statistically difference in 3-year disease-free survival

KRASG12C inhibitor sotorasib shows durable clinical benefits for solid cancers

Cancer Research - Second Edition eBook

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How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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Chemotherapy News and Research

Latest Chemotherapy News and Research

Cancer Research - Second Edition eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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