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New large-scale study maps early triggers of Alzheimer’s protein aggregation

A new large-scale study has mapped the first molecular events that drive the formation of harmful amyloid protein aggregates found in Alzheimer's disease, pointing towards a new potential therapeutic target.

12 Jun 2025

MIT study reveals flexible thinking behind everyday decisions

The human brain is very good at solving complicated problems. One reason for that is that humans can break problems apart into manageable subtasks that are easy to solve one at a time.

12 Jun 2025

Personalized model offers better blood pressure estimates from ankle measurements

A new method improving the accuracy of interpreting blood pressure measurements taken at the ankle could be crucial for people who cannot have their arm blood pressure measured.

12 Jun 2025

New open access tool could accelerate drug discovery

Scientists at Northwestern University have developed the largest open-access resource of its kind to help researchers shave off months of early-stage drug development time by allowing them to better understand diseases and find potential treatments.

12 Jun 2025

Exercise and omega-3 reduce oral inflammation in animal study

A study published in the journal Scientific Reports indicates that physical exercise combined with omega-3 supplementation considerably improves the immune response and reduces the severity of chronic apical periodontitis.

11 Jun 2025

Blocking a single enzyme rewires limb regrowth in axolotls

Researchers uncovered how CYP26B1-mediated retinoic acid (RA) breakdown determines segment identity during axolotl limb regeneration. Disrupting RA degradation reprograms blastema cells, revealing the molecular controls of precise limb regrowth.

11 Jun 2025

Why choosing different foods each day could lower your diabetes risk

A large European study found that consuming a greater variety of plant-based proteins, vegetables, and major food groups is linked to a lower risk of developing type 2 diabetes. The protective effect was strongest in women and individuals without central obesity.

11 Jun 2025

New hypothesis links caffeine to lower risk of sudden infant death syndrome

After decades of stalled national progress in reducing the rate of Sudden Unexpected Infant Death (SUID), a category of infant mortality that includes sudden infant death syndrome (SIDS), researchers at Rutgers Health have proposed an unexpected solution: Caffeine might protect babies by preventing dangerous drops in oxygen that may trigger deaths.

11 Jun 2025

Tufts researchers develop dental implant that mimics real tooth function

Each year, millions of people in the U.S. get dental implants as a long-term, natural-looking fix for missing teeth. But traditional implants don't fully mimic real teeth.

11 Jun 2025

Chikungunya vaccine could stop millions of infections worldwide, study finds

A landmark global modeling study reveals that more than 2.8 billion people in 104 countries are at risk of chikungunya, with up to 35 million infections annually. Strategic deployment of the IXCHIQ vaccine could prevent thousands of infections and deaths each year.

11 Jun 2025

New therapeutic approach targets PCSK9 to regulate blood cholesterol levels

When the amount of cholesterol in the blood is too high, hypercholesterolemia can develop, causing serious damage to the arteries and cardiovascular health.

11 Jun 2025

New 3D model reveals hidden role of stem cells in sense of smell

Using a newly devised, three-dimensional model to study the regeneration of nerve tissue in the nose, researchers at Tufts University School of Medicine and the Graduate School of Biomedical Sciences (GSBS) and colleagues have discovered that one type of stem cell thought to be dormant may play a more significant role in preserving the sense of smell than originally believed.

11 Jun 2025

Glucocorticoid receptor plays dual role in prostate cancer progression

A recent study from the Institute of Biomedicine at the University of Eastern Finland shows that the glucocorticoid receptor can both promote and inhibit prostate cancer progression, depending on the circumstances.

11 Jun 2025

Memory neurons in rats may explain why forgetting meals leads to overeating

Researchers identify "meal memory" neurons in laboratory rats that could explain why forgetting lunch leads to overeating.

11 Jun 2025

Smelling food triggers fullness through newly found brain pathway

No more hunger after cooking? A newly identified network of nerve cells is responsible, a research group at the Max Planck Institute for Metabolism Research has discovered in mice.

11 Jun 2025

Unexpected protein production in immune cells may fuel gut inflammation

Scientists have discovered that certain immune cells — called neutrophils — can start making a protein called DUOX2 that they usually do not produce.

11 Jun 2025

Antibiotic use predicts microbiota dysbiosis in preterm infants

Antibiotic use in preterm infants is linked to gut microbiome changes, increasing susceptibility to infections and impacting long-term health outcomes.

11 Jun 2025

‘Junk food’ plant diets raise heart risk even if meat is cut out

Research shows that healthy plant-based diets lower cardiac biomarkers, while unhealthy plant foods raise heart disease risk. Key findings from a large study.

11 Jun 2025

Maternal iron deficiency disrupts embryonic sex determination in mice

Developmentally expressed genes play a fundamental role in the formation of a wide range of organs. The Y chromosome-located mammalian sex-determining gene Sry, required for the formation of testis, is activated only within a narrow time window during embryogenesis.

11 Jun 2025

Tufts researchers design new generation of weight loss medications

Weight loss drugs like Ozempic and Wegovy are used by over 15 million adults in the U.S., or 4.5% of the population. Despite their effectiveness, they have drawbacks.

11 Jun 2025