Biochemistry

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New CRISPR-based assay can non-invasively detect a biomarker of acute kidney rejection in urine

When a patient receives a kidney transplant, doctors carefully monitor them for signs of rejection in several ways, including biopsy. However, this procedure is invasive and can only detect issues at a late stage.

5 Jan 2022

NRL researchers aim to advance understanding of how cells organize and communicate

U.S. Naval Research Laboratory researchers in the Chemistry Division apply their knowledge of biology in conjunction with materials to improve understanding of how cells and tissues organize and apply new methods to affect cell communication.

5 Jan 2022

Computational tools reveal how blood enzyme works at the atomic level

Membrane-associated proteins play a vital role in a variety of cellular processes, yet little is known about the membrane-association mechanism.

3 Jan 2022

New strategy to create a cheap and rapid COVID-19 test based on isothermal amplification

Russian researchers have developed a strategy to create a cheap and rapid COVID-19 test based on isothermal amplification. According to their publication in Applied Biochemistry and Microbiology, use of this strategy will make it possible to create universal test systems for any of the COVID-19 variants.

29 Dec 2021

Introducing deuterium makes drugs to have a longer effect

Hydrogen (abbreviated "H") is the lightest of all elements. It usually consists only of a positively charged proton and a negatively charged electron and is also called protium in this form. But there are also two heavier hydrogen isotopes, deuterium and tritium.

24 Dec 2021

New insights into how red meat-rich diet increases cardiovascular disease risk

A Cleveland Clinic-led study has revealed new insights into how a diet rich in red meat increases risk for cardiovascular disease. The findings were published in Nature Microbiology and build on more than a decade of research by lead author Stanley Hazen, MD, PhD.

23 Dec 2021

Eating sugar is healthy for some Greenlanders with a genetic variation

A genetic variation among some Greenlanders makes sugar healthy – significantly more than for most people.

22 Dec 2021

Researchers receive NIH grants to develop new treatments for neglected tropical diseases

Researchers at Washington University School of Medicine in St. Louis have received two grants from the National Institutes of Health totaling more than $5.5 million to develop new treatments for two types of devastating parasitic infections common in sub-Saharan Africa and Central and South America: river blindness and intestinal worm infections.

22 Dec 2021

Researchers discover new function of protein tBID

The protein tBID can trigger programmed cell death (apoptosis) by inducing damage in the energy suppliers of the cells, the mitochondria. Apoptosis is essential for maintaining tissue balance.

21 Dec 2021

Research reveals the structure and function of a bifunctional protein that transports heme

Heme is an essential part of the protein hemoglobin, which colors human blood red. Heme also is crucial for cytochrome proteins, which power the cell. Humans, animals, plants and bacteria all use heme.

21 Dec 2021

New study shows how regular exercise protects against fatty liver disease

Exercise not only trains the muscles but can also prevent the development of fatty liver. A new study by the German Center for Diabetes Research, Helmholtz Munich and Tübingen University Hospital shows which molecular adaptations, in particular of the liver mitochondria, can be observed in this process.

20 Dec 2021

UBR7 protein acts as a histone chaperone during DNA replication, study finds

The protein UBR7 acts as a histone chaperone, regulating histone re-deposition at specific sites during DNA replication, according a recent study published in The EMBO Journal.

20 Dec 2021

Traditional medicinal plant alleviates malaria symptoms in mice

The active plant ingredient anemonin could provide a new approach in the treatment of malaria. It was identified by researchers from Ethiopia and Germany in a buttercup that is traditionally used in some African countries as a medicinal plant to treat malaria.

20 Dec 2021

Succinate receptor can be a potential target for cancer treatment

Cancer cells show unchecked rapid growth beyond tissue boundaries that is no longer stopped by normal control mechanisms. Due to this rapid growth, the metabolism of cancer cells is altered compared to that of cells that grow normally.

18 Dec 2021

Specific diets have less effect on IBS symptoms than expected

Many IBS sufferers avoid certain types of food and often exclude gluten. However, a large new study from Chalmers University of Technology and Uppsala University, Sweden, does not show a relationship between high intake of gluten and increased IBS symptoms.

16 Dec 2021

Biochemistry

New CRISPR-based assay can non-invasively detect a biomarker of acute kidney rejection in urine

NRL researchers aim to advance understanding of how cells organize and communicate

Computational tools reveal how blood enzyme works at the atomic level

New strategy to create a cheap and rapid COVID-19 test based on isothermal amplification

Introducing deuterium makes drugs to have a longer effect

New insights into how red meat-rich diet increases cardiovascular disease risk

Eating sugar is healthy for some Greenlanders with a genetic variation

Researchers receive NIH grants to develop new treatments for neglected tropical diseases

Researchers discover new function of protein tBID

Research reveals the structure and function of a bifunctional protein that transports heme

New study shows how regular exercise protects against fatty liver disease

UBR7 protein acts as a histone chaperone during DNA replication, study finds

Traditional medicinal plant alleviates malaria symptoms in mice

Succinate receptor can be a potential target for cancer treatment

Specific diets have less effect on IBS symptoms than expected

Mutations in histone regulator protein linked to rare neurodevelopmental disorder, cancers

Novel imaging method used to map glycosylation patterns linked with Alzheimer’s disease

Researchers take advantage of virus' sweet tooth in the design of sugar-coated COVID-19 test strip

Interaction between SARS-CoV-2 N-protein and Parkinson's protein speeds up amyloid formation

New copper surface could help fight antibiotic-resistant superbugs

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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