Biochemistry

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Naturally-occurring compound found in trees effective in fighting superbugs

Researchers at the University of Portsmouth have discovered that a naturally-occurring compound found in trees is effective in combating superbugs.

22 Mar 2023

High-fat and high-sugar foods can rewire the brain

Chocolate bars, crisps and fries - why can't we just ignore them in the supermarket? Researchers at the Max Planck Institute for Metabolism Research in Cologne, in collaboration with Yale University, have now shown that foods with a high fat and sugar content change our brain: If we regularly eat even small amounts of them, the brain learns to consume precisely these foods in the future.

22 Mar 2023

Gyros Protein Technologies introduces new PurePep EasyClean services to accelerate development and manufacturing of peptide-based drugs

Gyros Protein Technologies AB today announced the launch of three service offerings to support development and manufacturing of peptide-based drugs.

From Gyros Protein Technologies AB 22 Mar 2023

AI-based design method synthesizes polymers that mimic blood plasma

Most life on Earth is based on polymers of 20 amino acids that have evolved into hundreds of thousands of different, highly specialized proteins. They catalyze reactions, form backbone and muscle and even generate movement.

20 Mar 2023

Research shows the role of PCYT2-mediated lipid synthesis in vertebrate muscle health

Muscle degeneration, the most prevalent cause of frailty in hereditary diseases and aging, could be caused by a deficiency in one key enzyme in a lipid biosynthesis pathway.

20 Mar 2023

Molecular basis for alkaline taste discovered

The sense of taste is among the first to come into contact with food before we ingest it, but whether animals can taste basic or alkaline food and how they do it remained unclear until now.

20 Mar 2023

Novel RNA sense-and-respond circuit harnesses the force of enzymes to develop better drugs

More than twelve billion doses of mRNA vaccines have been administered globally since the start of the COVID pandemic, saving millions of lives. But RNA-based therapies for other diseases have so far proven more challenging to develop.

20 Mar 2023

How the structural and functional effects of mutations on androgen receptor lead to prostate cancer

The androgen receptor is a key transcriptional factor for the proper sex development —specially in males— and the physiological balance of all the tissues that express this receptor.

17 Mar 2023

Multiplex PCR panels associated with reduced administration of antibiotics to hospitalized GI patients

Acute gastroenteritis afflicts adults of all ages, causing significant suffering and inflicting significant costs on the American healthcare system.

16 Mar 2023

Purine metabolite xanthine may play a role in Th17 cell differentiation in the gut

The gut is home to a cast of microbes that influence health and disease. Some types of microorganisms are thought to contribute to the development of inflammatory conditions, such as inflammatory bowel disease (IBD), but the exact cascade of events that leads from microbes to immune cells to disease remains mysterious.

16 Mar 2023

PBD Biotech’s new lyophilized PCR reaction bead offers easy ambient shipping, extends global reach of active TB test

Tuberculosis testing and treatment needs to happen close to the point of infection. PBD Biotech has developed a lyophilized PCR reaction bead for its Actiphage® blood test for active TB.

16 Mar 2023

Chemists reveal a whole new role for molecular mirroring

With the aid of some sea slugs, University of Nebraska–Lincoln chemists have discovered that one of the smallest conceivable tweaks to a biomolecule can elicit one of the grandest conceivable consequences: directing the activation of neurons.

15 Mar 2023

High consumption of common artificial sweetener lowers activation of T-cells in mice

Scientists at the Francis Crick Institute have found that high consumption of a common artificial sweetener, sucralose, lowers activation of T-cells, an important component of the immune system, in mice.

15 Mar 2023

New biomimetic model helps study wound healing in burn and laceration wounds

Burn wounds are notoriously prone to bacterial infection and typically lead to a larger amount of scar tissue than laceration wounds.

15 Mar 2023

‘Glow-in-the-dark’ proteins could make disease diagnosis quicker and easier

Despite recent advancements, many highly sensitive diagnostic tests for viral diseases still require complicated techniques to prepare a sample or interpret a result, making them impractical for point-of-care settings or areas with few resources.

15 Mar 2023

Reversing infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein

Houston Methodist scientists reversed infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein, showing further evidence that links high cholesterol to female infertility.

15 Mar 2023

Women-focused diagnostics start-up wins INTEGRA Biosciences’ EVOLVE pipettes

Nanopath has been chosen as the first winner of the recently launched INTEGRA supports start-ups competition.

From INTEGRA Biosciences 15 Mar 2023

Study paves way for developing effective ASO therapies for brain diseases with fewer side effects

A promising therapy for a range of brain diseases involves antisense oligonucleotides (ASOs) - specialized molecules that can modulate RNA and alter protein production - directly injected into the cerebrospinal fluid, in the space around the brain and spinal cord.

14 Mar 2023

Understanding how cells adjust in real time to withstand stresses on our health

Every minute of every day, our body adapts to meet the needs of each moment. When we binge on carbs, exercise, or become sick, chemical reactions inside our cells switch on, slow down, or shift strategy so that we have the energy and strength we need.

14 Mar 2023

Wayne State team discovers a simple technology to detect active TB infection antibodies

A team of faculty from Wayne State University has discovered new technology that will quickly and easily detect active Mycobacterium tuberculosis (TB) infection antibodies.

13 Mar 2023

Biochemistry

Naturally-occurring compound found in trees effective in fighting superbugs

High-fat and high-sugar foods can rewire the brain

Gyros Protein Technologies introduces new PurePep EasyClean services to accelerate development and manufacturing of peptide-based drugs

AI-based design method synthesizes polymers that mimic blood plasma

Research shows the role of PCYT2-mediated lipid synthesis in vertebrate muscle health

Molecular basis for alkaline taste discovered

Novel RNA sense-and-respond circuit harnesses the force of enzymes to develop better drugs

How the structural and functional effects of mutations on androgen receptor lead to prostate cancer

Multiplex PCR panels associated with reduced administration of antibiotics to hospitalized GI patients

Purine metabolite xanthine may play a role in Th17 cell differentiation in the gut

PBD Biotech’s new lyophilized PCR reaction bead offers easy ambient shipping, extends global reach of active TB test

Chemists reveal a whole new role for molecular mirroring

High consumption of common artificial sweetener lowers activation of T-cells in mice

New biomimetic model helps study wound healing in burn and laceration wounds

‘Glow-in-the-dark’ proteins could make disease diagnosis quicker and easier

Reversing infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein

Women-focused diagnostics start-up wins INTEGRA Biosciences’ EVOLVE pipettes

Study paves way for developing effective ASO therapies for brain diseases with fewer side effects

Understanding how cells adjust in real time to withstand stresses on our health

Wayne State team discovers a simple technology to detect active TB infection antibodies

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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